Specialist – Bioanalysis

Job Description

Specialist – Bioanalysis (In Vitro DMPK)

Job Role: Specialist – Bioanalysis (In Vitro DMPK)
Location: Bengaluru
Experience: 8–15 Years
Qualification: M.Pharm

Job Summary

We are seeking an experienced Specialist – Bioanalysis (In Vitro DMPK) to lead bioanalytical activities supporting drug discovery and development. The role involves executing advanced ADME/DMPK studies, operating LC-MS/MS systems, optimizing laboratory workflows, and mentoring junior scientists.

Key Responsibilities
LC-MS/MS Bioanalysis
Serve as the technical expert for LC-MS/MS operation, maintenance, and troubleshooting.
Perform bioanalytical sample analysis for ADME studies.
In Vitro ADME Assays

Execute and analyze assays including:

Permeability Studies
Caco-2
MDCK
PAMPA
Metabolic Stability
Hepatocyte Stability
Microsomal Stability
CYP Inhibition
Physicochemical & Stability Studies
High-throughput Solubility
Plasma Stability
Buffer Stability
SGF Stability
SIF Stability
Physicochemical Profiling
Conduct:
Kinetic Solubility
Thermodynamic Solubility
Chromatographic Log D studies
Metabolite Identification (MET-ID)
Analyze metabolite identification samples.
Prepare comprehensive technical reports.
Laboratory Operations
Optimize bioanalytical workflows to ensure timely project delivery.
Mentor and train junior scientists on laboratory techniques and bioanalytical methods.
Eligibility
Qualification: M.Pharm.
Experience: 8–15 years in Bioanalysis with a strong focus on DMPK/ADME studies.
Experience in a Pharmaceutical or CRO environment is preferred.
Strong expertise in LC-MS/MS-based bioanalytical techniques.
Technical Skills
LC-MS/MS
In Vitro ADME
DMPK
Bioanalysis
Metabolic Stability Studies
Permeability Assays (Caco-2, MDCK, PAMPA)
CYP Inhibition
MET-ID
Solubility & Stability Studies
Scientific Reporting
Team Mentoring
How to Apply

📧 Email: krishnafulsure@aurigeneservices.com